Neck, shoulder, and jaw tightness are common signs of stress, fatigue, and muscle strain. While stretching and good posture help, many people are turning to CBD-infused lotions to complement their tension-relief routine. Cannabidiol (CBD), the non-psychoactive compound from hemp, is being studied for its anti-inflammatory and muscle-soothing benefits when applied topically.

Research from Harvard Health and the National Library of Medicine notes that CBD interacts with local receptors in the skin’s endocannabinoid system, potentially reducing inflammation and discomfort. Although more studies are needed, early findings suggest topical CBD may help relax tight muscles and improve mobility.

When selecting a CBD lotion, look for third-party lab testing, clear labeling of CBD content, and skin-friendly ingredients such as arnica, menthol, or magnesium. Below are five reputable options designed to target soreness and muscle tension around the neck, shoulders, and jawline.

1. Myaderm Advanced Therapy Fast Acting Relief Cream

Price: $29.99 | Rating: 4.5 ★ | CBD Type: Broad-spectrum

Myaderm’s Advanced Therapy Cream is formulated for fast-acting relief and deep tissue absorption. It’s a go-to option for athletes and individuals managing chronic neck or shoulder tension. The lightweight, non-greasy texture allows easy daily use without residue. It’s also pharmacist-developed and tested for purity.

2. Irwin Naturals CBD Balm 1000 mg

Price: $49.99 | Rating: 4.8 ★ | CBD Type: Full-spectrum

Available through CVS Pharmacy, Irwin Naturals’ CBD Balm provides a potent 1000 mg formula ideal for deeper muscle areas like the trapezius or jawline. Its nourishing base and high CBD concentration make it suitable for end-of-day relaxation or after workouts when stiffness peaks.

3. NOW Solutions CBD Extra Strength Balm

Price: $17.49 | Rating: 5.0 ★ | CBD Type: Isolate

For those seeking an affordable yet effective option, NOW Solutions offers a simple formula free of harsh additives. It provides targeted relief for mild tension or daily maintenance. Ideal for individuals sensitive to essential oils or menthol, it’s gentle enough for the jaw and upper neck area.

4. Irwin Naturals CBD Cream + Menthol

Price: $49.99 | Rating: 4.8 ★ | CBD Type: Full-spectrum

This variation adds menthol for a cooling sensation that helps relieve heat and swelling in sore muscles. The combination of full-spectrum CBD and menthol makes it a strong pick for tension headaches or TMJ-related tightness in the jaw. It absorbs quickly and can be massaged gently into problem areas.

5. Function Botanicals 1200 mg CBD + Magnesium Cream

Price: $60.00 | CBD Type: Full-spectrum

Function Botanicals merges CBD with magnesium, a mineral known for muscle relaxation. This high-strength cream (1200 mg) works well for persistent stiffness or after physical activity. It’s free of artificial fragrance and features clean, natural ingredients — great for sensitive skin around the neck and jaw.

Everyday Relief

CBD lotions can be a simple yet effective way to manage tension in delicate areas like the neck, shoulders, and jaw. While results vary, many users report relief from stiffness and stress when combining CBD topicals with stretching, hydration, and good posture.

Among these, Myaderm and Function Botanicals stand out for potency, while NOW Solutions offers great value for everyday use. Whichever you choose, verify lab testing and ingredient transparency—key signs of a trustworthy CBD brand.